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JACHO Notice
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GERD
(Gastro
Esophageal Reflux Disease)
Overview
GERD
is an acronym for a very common condition called "Gastroesophageal Reflux
Disease." It is a disease that is suffered by millions of Americans. Patients
with GERD experience a reflux of acid into their esophageal tract. The most
common symptom of GERD is heartburn, a burning sensation just below the heart,
which occurs right after a big meal; however, in some cases GERD is caused by
physiological irregularities which are very serious and can be quite painful if
left untreated.
Your gastrointestinal tract includes a number of organs
that aid in the process of digestion. The esophagus is a long tube, which
begins at the pharynx and ends at the diaphragm. It's actions are controlled
through a combination of muscle and nerve activity. The primary function of the
esophagus is to move food toward the stomach by swallowing (peristalsis). Once
the food has passed into the stomach the esophagus also prevents food and
stomach acid from regurgitating by using the Lower-Esophageal Sphincter (LES).
The LES is an area of thickness located at the end of the esophageal tract,
right before the entry into the stomach. After peristalsis, the LES tightens
preventing the reflux of food and acid. The dominant cause of GERD is due to
improper LES function.
Should any material be regurgitated back into the
esophageal tract, it will be cleared through a process of secondary
peristalsis. In some patients suffering from GERD, stomach acid can remain in
the esophageal tract for several hours because of ineffective secondary
peristalsis.
In addition to improper LES function, there are certain
physiological and lifestyle factors that can also increase the incidence of
GERD. Two physiological factors include:
 | Decreased salivation: your saliva contains
bicarbonate, a substance that neutralizes stomach acid. If you are not
producing enough saliva to properly coat your food, stomach acid will remain
potent and caused prolonged acid exposure to the esophageal tract.
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 | Impaired tissue resistance: the lining of your
esophageal tract is designed to protect itself from stomach acid. It also
produces bicarbonate to neutralize the acid. In some patients, this built-in
protection system operates ineffectively, thereby causing GERD. This factor
is more common in patients over the age of 40. |
There are several lifestyle risk factors that can
increase the incidence of GERD:
 | Smoking |
 | Large meals |
 | Fatty foods |
 | Caffeine |
 | Pregnancy |
 | Obesity |
 | Body position |
 | Hormones |
Symptoms
GERD can have multiple effects on various parts of the
body. Symptoms can be pulmonary, digestive or oral depending on the severity
and duration of the case. Here are some of the most of the symptoms associated
with GERD:
 | Heartburn: this is the most common symptom of GERD.
This symptoms is associated with a burning sensation just below the heart and
is caused by a reflux of extremely potent acid into the esophageal tract.
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 | Regurgitation: caused by the reflux of acid and
gastric contents into the esophageal tract. |
 | Dysfunctional Swallowing: dysphagia (difficulty
swallowing) and odynophagia (pain swallowing) are both symptoms of GERD.
Dysphagia is caused by either inflammation, abnormal peristalsis, or
stricture. Dysphagia can also be a symptom
of esophageal cancer. Odynophagia is caused by erosive esophagitis which can
be caused either by bacterial infection or medication. |
 | Chest Pain: the pain can radiate throughout the
chest, neck and arms with varying intensity. |
Pulmonary symptoms which occur in a smaller percentage
of people with GERD are caused by acid reflux past the upper esophageal
sphincter. This type of symptom includes:
Oral symptoms include:
 | waterbrash: spontaneous appearance of saliva in the
mouth |
 | gingivitis |
 | tooth decay |
Diagnosis
If
you or your physician suspects that you are suffering from GERD, then endoscopy
will be used to determine the damage to your esophageal tract. There are
several types of abnormalities associated with GERD all of which can be
classified, generally, as a subset of a condition called
esophagitis. Using
endoscopy your physician will inspect your
esophageal tract in order to determine the severity of your condition. Here are
the different classifications associated with esophageal damage associated with
GERD:
 | erythema: redness of the esophageal lining.
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 | isolated erosions |
 | confluent erosions |
 | circumferential erosions |
 | stricture |
 | Barrett's Esophagus: replacement of normal "squamous"
lining of esophagus with columnar lining. |
Treatment
GERD can usually be treated by making lifestyle or diet
modifications. If you are suffering from GERD or heartburn you should consult a
physician. In addition to your consultation try the following tips to reduce
the incidence of reflux:
 | Avoid lying down right after eating and within two
to three hours of bedtime. |
 | Elevate the head of the bed four to six inches.
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 | Lose weight if overweight. |
 | Stop smoking. |
 | Avoid eating large meals. Instead, eat smaller, more
frequent meals. |
 | Avoid:
- Chocolate
- Coffee and alcohol
- Fried and fatty foods
- Mint products (i.e., peppermint, spearmint)
- Carbonated beverages, and citrus fruits or juices
- Tomato sauce, ketchup, mustard and vinegar
- Aspirin and most pain medicines (other than
acetaminophen).
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If diet and lifestyle changes are not enough to control
GERD, then medications can be prescribed. Most medications treating GERD fall
into two categories: H2Blockers or the more potent Proton Pump
Inhibitors (PPIs).
H2 Blockers
Most H2 Blockers work by decreasing the flow of stomach
acid and are available without a prescription. H2 Blockers should be used to
treat mild cases of heartburn. Consult your physician if over-the-counter H2
Blockers have not been effective.
Proton Pump Inhibitors
PPIs work by helping the esophagus heal faster (within
6 to 8 weeks), thereby decreasing the duration of pain associated with reflux.
This type of medication is more potent than H2 Blockers and may require a
prescription.
The following is a list of medications used to treat
GERD:
 | Aciphex (PPI): requires a prescription. Other
similar drugs are Prevacid, Prilosec, Nexium and Protonix. |
 | Carafate: prescription required. |
 | Pepcid (H2 Blocker): available with or without a
prescription |
 | Propulsid: prescription required. Note: The FDA has
issued a warning that Propulsid may cause cardiac arrhythmia. |
 | Reglan: available without a prescription
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 | Tagamet (H2 Blocker): available with or without a
prescription. |
In some cases, when medications have proven to be
ineffective, the patient must live on medications or if surgery is the only
viable option, a physician will use a procedure called a
Nissen
Fundoplication to treat GERD.

"Heartburn." The American Gastroenterology
Association of America. 2002.
"GERD." GERD Information Resource Center. 2002. <http://www.gerd.com>
22 Mar. 2002
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